Sex differences in apolipoprotein A1 and nevirapine-induced toxicity

Nevirapine (NVP) is associated with severe liver and skin toxicity through sulfotransferase (SULT) bioactivation of the phase I metabolite 12-hydroxy-NVP [1–3]. The female sex, a well-known risk factor for NVP-induced toxicity, is associated with higher SULT expression [4] and lower plasma levels of...

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Dettagli Bibliografici
Pubblicato in:J Int AIDS Soc
Autori principali: Marinho, Aline, Dias, Clara, Antunes, Alexandra, Caixas, Umbelina, Branco, Teresa, Marques, Matilde, Monteiro, Emília, Pereira, Sofia
Natura: Artigo
Lingua:Inglês
Pubblicazione: International AIDS Society 2014
Soggetti:
Poster Sessions – Abstract P043
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224844/
https://ncbi.nlm.nih.gov/pubmed/25394082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7448/IAS.17.4.19575
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