Spatial proteomics revealed a CX(3)CL1-dependent crosstalk between the urothelium and relocated macrophages through IL-6 during an acute bacterial infection in the urinary bladder

The urothelium of the urinary bladder represents the first line of defense. However, uropathogenic E. coli (UPEC) damage the urothelium and cause acute bacterial infection. Here, we demonstrate the crosstalk between macrophages and the urothelium stimulating macrophage migration into the urothelium....

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Publicado en:Mucosal Immunol
Main Authors: Bottek, Jenny, Soun, Camille, Lill, Julia K., Dixit, Akanksha, Thiebes, Stephanie, Beerlage, Anna-Lena, Horstmann, Marius, Urbanek, Annett, Heuer, Heike, Uszkoreit, Julian, Eisenacher, Martin, Bracht, Thilo, Sitek, Barbara, Hoffmann, Franziska, Vijitha, Nirojah, von Eggeling, Ferdinand, Engel, Daniel R.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group US 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312419/
https://ncbi.nlm.nih.gov/pubmed/32112048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-020-0269-7
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