The Effect of Sodium Bicarbonate, a Beneficial Adjuvant Molecule in Cystic Fibrosis, on Bronchial Epithelial Cells Expressing a Wild-Type or Mutant CFTR Channel

Clinical and experimental results with inhaled sodium bicarbonate as an adjuvant therapy in cystic fibrosis (CF) are promising due to its mucolytic and bacteriostatic properties, but its direct effect has not been studied on respiratory epithelial cells. Our aim was to establish and characterize co-...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Gróf, Ilona, Bocsik, Alexandra, Harazin, András, Santa-Maria, Ana Raquel, Vizsnyiczai, Gaszton, Barna, Lilla, Kiss, Lóránd, Fűr, Gabriella, Rakonczay, Zoltán, Ambrus, Rita, Szabó-Révész, Piroska, Gosselet, Fabien, Jaikumpun, Pongsiri, Szabó, Hajnalka, Zsembery, Ákos, Deli, Mária A.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312297/
https://ncbi.nlm.nih.gov/pubmed/32512832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21114024
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