Optimization of a combined wet milling process in order to produce poly(vinyl alcohol) stabilized nanosuspension

PURPOSE: The article reports a wet milling process, where the planetary ball mill was combined with pearl milling technology to reach nanosize range of meloxicam (Mel; 100–500 nm). The main purpose was to increase the dissolution rate and extent of a poorly water-soluble Mel as nonsteroidal anti-inf...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Bartos, Csaba, Jójárt-Laczkovich, Orsolya, Katona, Gábor, Budai-Szűcs, Mária, Ambrus, Rita, Bocsik, Alexandra, Gróf, Ilona, Deli, Mária Anna, Szabó-Révész, Piroska
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987755/
https://ncbi.nlm.nih.gov/pubmed/29910603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S159965
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