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Maternal Immune Activation Induces Neuroinflammation and Cortical Synaptic Deficits in the Adolescent Rat Offspring

Maternal immune activation (MIA), induced by infection during pregnancy, is an important risk factor for neuro-developmental disorders, such as autism. Abnormal maternal cytokine signaling may affect fetal brain development and contribute to neurobiological and behavioral changes in the offspring. H...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Cieślik, Magdalena, Gąssowska-Dobrowolska, Magdalena, Jęśko, Henryk, Czapski, Grzegorz A., Wilkaniec, Anna, Zawadzka, Aleksandra, Dominiak, Agnieszka, Polowy, Rafał, Filipkowski, Robert K., Boguszewski, Paweł M., Gewartowska, Magdalena, Frontczak-Baniewicz, Małgorzata, Sun, Grace Y., Beversdorf, David Q., Adamczyk, Agata
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312084/
https://ncbi.nlm.nih.gov/pubmed/32521803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21114097
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