Germline and Somatic Pharmacogenomics to Refine Rectal Cancer Patients Selection for Neo-Adjuvant Chemoradiotherapy

Neoadjuvant chemoradiotherapy (nCRT) followed by radical surgery is the standard of care for patients with Locally Advanced Rectal Cancer (LARC). Current selection for nCRT is based on clinical criteria regardless of any molecular marker. Pharmacogenomics may be a useful strategy to personalize and...

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Publicat a:Front Pharmacol
Autors principals: De Mattia, Elena, Roncato, Rossana, Palazzari, Elisa, Toffoli, Giuseppe, Cecchin, Erika
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311751/
https://ncbi.nlm.nih.gov/pubmed/32625092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00897
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