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Germline and Somatic Pharmacogenomics to Refine Rectal Cancer Patients Selection for Neo-Adjuvant Chemoradiotherapy

Neoadjuvant chemoradiotherapy (nCRT) followed by radical surgery is the standard of care for patients with Locally Advanced Rectal Cancer (LARC). Current selection for nCRT is based on clinical criteria regardless of any molecular marker. Pharmacogenomics may be a useful strategy to personalize and...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: De Mattia, Elena, Roncato, Rossana, Palazzari, Elisa, Toffoli, Giuseppe, Cecchin, Erika
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311751/
https://ncbi.nlm.nih.gov/pubmed/32625092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00897
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