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BRAFV600E expression in neural progenitors results in a hyperexcitable phenotype in neocortical pyramidal neurons

Somatic mutations have emerged as the likely cause of focal epilepsies associated with developmental malformations and epilepsy-associated glioneuronal tumors (GNT). Somatic BRAFV600E mutations in particular have been detected in the majority of low-grade neuroepithelial tumors (LNETS) and in neuron...

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Detalhes bibliográficos
Publicado no:J Neurophysiol
Main Authors: Goz, Roman U., Akgül, Gülcan, LoTurco, Joseph J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311733/
https://ncbi.nlm.nih.gov/pubmed/32401131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00523.2019
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