Differential effects of REV-ERBα/β agonism on cardiac gene expression, metabolism, and contractile function in a mouse model of circadian disruption

Cell-autonomous circadian clocks have emerged as temporal orchestrators of numerous biological processes. For example, the cardiomyocyte circadian clock modulates transcription, translation, posttranslational modifications, ion homeostasis, signaling cascades, metabolism, and contractility of the he...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Mia, Sobuj, Kane, Mariame S., Latimer, Mary N., Reitz, Cristine J., Sonkar, Ravi, Benavides, Gloria A., Smith, Samuel R., Frank, Stuart J., Martino, Tami A., Zhang, Jianhua, Darley-Usmar, Victor M., Young, Martin E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311693/
https://ncbi.nlm.nih.gov/pubmed/32357113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00709.2019
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