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High expression of spliced X-Box Binding Protein 1 in lung tumors is associated with cancer aggressiveness and epithelial-to-mesenchymal transition

Proteostasis imbalance is emerging as a major hallmark of cancer, driving tumor growth and aggressiveness. Endoplasmic Reticulum (ER) stress has been documented in most major cancers, and the ability to tolerate persistent ER stress through an effective unfolded protein response enhances cancer cell...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tavernier, Quentin, Legras, Antoine, Didelot, Audrey, Normand, Corinne, Gibault, Laure, Badoual, Cécile, Le Pimpec-Barthes, Françoise, Puig, Pierre Laurent, Blons, Hélène, Pallet, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311525/
https://ncbi.nlm.nih.gov/pubmed/32576923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67243-8
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