High expression of spliced X-Box Binding Protein 1 in lung tumors is associated with cancer aggressiveness and epithelial-to-mesenchymal transition

Proteostasis imbalance is emerging as a major hallmark of cancer, driving tumor growth and aggressiveness. Endoplasmic Reticulum (ER) stress has been documented in most major cancers, and the ability to tolerate persistent ER stress through an effective unfolded protein response enhances cancer cell...

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Udgivet i:Sci Rep
Main Authors: Tavernier, Quentin, Legras, Antoine, Didelot, Audrey, Normand, Corinne, Gibault, Laure, Badoual, Cécile, Le Pimpec-Barthes, Françoise, Puig, Pierre Laurent, Blons, Hélène, Pallet, Nicolas
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311525/
https://ncbi.nlm.nih.gov/pubmed/32576923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67243-8
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