Two novel fish paralogs provide insights into the Rid family of imine deaminases active in pre-empting enamine/imine metabolic damage

Reactive Intermediate Deaminase (Rid) protein superfamily includes eight families among which the RidA is conserved in all domains of life. RidA proteins accelerate the deamination of the reactive 2-aminoacrylate (2AA), an enamine produced by some pyridoxal phosphate (PLP)-dependent enzymes. 2AA acc...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Digiovanni, Stefania, Visentin, Cristina, Degani, Genny, Barbiroli, Alberto, Chiara, Matteo, Regazzoni, Luca, Di Pisa, Flavio, Borchert, Andrew J., Downs, Diana M., Ricagno, Stefano, Vanoni, Maria Antonietta, Popolo, Laura
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311433/
https://ncbi.nlm.nih.gov/pubmed/32576850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66663-w
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