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Antifibrotic role of low-dose mitomycin-c-induced cellular senescence in trabeculectomy models
PURPOSE: We assessed whether mitomycin-C (MMC) has different antifibrotic mechanisms in trabeculectomy wound healing. METHODS: We identified 2 concentrations of MMC as “low-dose” by using WST-1 assay, Lactic dehydrogenase assay, and fluorescence-activated cell sorting flow cytometry. Senescence-asso...
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| Publicado en: | PLoS One |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7310836/ https://ncbi.nlm.nih.gov/pubmed/32574191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0234706 |
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