Single-cell transcriptomic analysis of SARS-CoV-2 reactive CD4 (+) T cells

The contribution of CD4 (+) T cells to protective or pathogenic immune responses to SARS-CoV-2 infection remains unknown. Here, we present large-scale single-cell transcriptomic analysis of viral antigen-reactive CD4 (+) T cells from 32 COVID-19 patients. In patients with severe disease compared to...

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Meckiff, Benjamin J., Ramírez-Suástegui, Ciro, Fajardo, Vicente, Chee, Serena J, Kusnadi, Anthony, Simon, Hayley, Grifoni, Alba, Pelosi, Emanuela, Weiskopf, Daniela, Sette, Alessandro, Ay, Ferhat, Seumois, Grégory, Ottensmeier, Christian H, Vijayanand, Pandurangan
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7310619/
https://ncbi.nlm.nih.gov/pubmed/32587963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.06.12.148916
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