Ablation of endothelial Pfkfb3 protects mice from acute lung injury in LPS-induced endotoxemia

Acute lung injury (ALI) is one of the leading causes of death in sepsis. Endothelial inflammation and dysfunction play a prominent role in development of ALI. Glycolysis is the predominant bioenergetic pathway for endothelial cells (ECs). However, the role of EC glycolysis in ALI of sepsis remains u...

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Vydáno v:Pharmacol Res
Hlavní autoři: Wang, Lina, Cao, Yapeng, Gorshkov, B, Zhou, Yaqi, Yang, Qiuhua, Xu, Jiean, Ma, Qian, Zhang, Xiaoyu, Wang, Jingjing, Mao, Xiaoxiao, Zeng, Xianqiu, Su, Yunchao, Verin, AD, Hong, Mei, Liu, Zhiping, Huo, Yuqing
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7310404/
https://ncbi.nlm.nih.gov/pubmed/31167111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2019.104292
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