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Impacts of drug resistance mutations on the structural asymmetry of the HIV-2 protease
BACKGROUND: Drug resistance is a severe problem in HIV treatment. HIV protease is a common target for the design of new drugs for treating HIV infection. Previous studies have shown that the crystallographic structures of the HIV-2 protease (PR2) in bound and unbound forms exhibit structural asymmet...
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| Publicado no: | BMC Mol Cell Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7310402/ https://ncbi.nlm.nih.gov/pubmed/32576133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-020-00290-1 |
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