Amplification of KRAS and its heterogeneity in non-Asian gastric adenocarcinomas

BACKGROUND: Gastric cancer is one of the deadliest cancer entities worldwide. While surgery is the only curative treatment option in early tumors, for locally advanced and metastatic patients further therapeutic targets are needed. Several studies not only reported mutations but also amplifications...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Rehkaemper, Jan, Korenkov, Michael, Quaas, Alexander, Rueschoff, Josef, Pamuk, Aylin, Zander, Thomas, Hillmer, Axel M., Buettner, Reinhard, Hoelscher, Arnulf Heinrich, Bruns, Christiane Josephine, Loeser, Heike, Alakus, Hakan, Schoemig-Markiefka, Birgid
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7310377/
https://ncbi.nlm.nih.gov/pubmed/32571252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-06996-x
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