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A double-blind, placebo-controlled, phase II, randomized study of lovastatin therapy in the treatment of mildly active rheumatoid arthritis

OBJECTIVES: 3-hydroxy-3-methylglutaryl coenzyme-A (HMG Co-A) reductase inhibitors (statins) are standard treatment for hyperlipidaemia. In addition to lipid-lowering abilities, statins exhibit multiple anti-inflammatory effects. The objectives of this study were to determine whether treatment of pat...

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Pubblicato in:Rheumatology (Oxford)
Autori principali: Aranow, Cynthia, Cush, John, Bolster, Marcy B, Striebich, Christopher C, Dall’era, Maria, Mackay, Meggan, Olech, Ewa, Frech, Tracy, Box, Jane, Keating, Richard, Wasko, Mary Chester, St Clair, William, Kivitz, Alan, Huang, Weiquang, Ricketts, PetaGay, Welch, Beverly, Callahan, Sherrie, Spychala, Meagan, Boyle, Karen, York, Kate, Keyes-Elstein, Lynette, Goldmuntz, Ellen, Diamond, Betty, Davidson, Anne
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7310095/
https://ncbi.nlm.nih.gov/pubmed/31628482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/kez471
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