Double-Blind Randomized Placebo-Controlled Trial of the Effect of Vitamin D3 on the Interferon Signature in Patients with Systemic Lupus Erythematosus

OBJECTIVE: Vitamin D modulates the immune response and blocks induction of an interferon signature by SLE sera. We investigated the effects of vitamin D supplementation on the IFN signature in SLE patients. METHODS: 57 SLE patients with stable, inactive disease, a serum 25OH vitamin D (25OHD) ≤20ng/...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Aranow, Cynthia, Kamen, Diane L., Dall'Era, Maria, Massarotti, Elena M., Mackay, Meggan C., Koumpouras, Fotios, Coca, Andreea, Chatham, W. Winn, Clowse, Megan E. B., Criscione-Schreiber, Lisa G., Callahan, Sherri, Goldmuntz, Ellen A., Keyes-Elstein, Lynette, Oswald, Michaela, Gregersen, Peter K., Diamond, Betty
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732716/
https://ncbi.nlm.nih.gov/pubmed/25777546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39108
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