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Isotopic labeling of eukaryotic membrane proteins for NMR studies of interactions and dynamics

Membrane proteins, and especially G-protein coupled receptors (GPCRs), are increasingly important targets of structural biology studies due to their involvement in many biomedically-critical pathways in humans. These proteins are often highly dynamic and thus benefit from studies by NMR spectroscopy...

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Detalhes bibliográficos
Publicado no:Methods Enzymol
Main Authors: Dikiy, Igor, Clark, Lindsay D., Gardner, Kevin H., Rosenbaum, Daniel M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7309954/
https://ncbi.nlm.nih.gov/pubmed/30611431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2018.08.030
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