Differential Regulation of l-Arginine Metabolism through Arginase 1 during Infection with Leishmania mexicana Isolates Obtained from Patients with Localized and Diffuse Cutaneous Leishmaniasis

l-Arginine metabolism through arginase 1 (Arg-1) and inducible nitric oxide synthase (NOS2) constitutes a fundamental axis for the resolution or progression of leishmaniasis. Infection with Leishmania mexicana can cause two distinct clinical manifestations: localized cutaneous leishmaniasis (LCL) an...

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Udgivet i:Infect Immun
Main Authors: Wilkins-Rodríguez, Arturo A., Pérez-Torres, Armando, Escalona-Montaño, Alma R., Gutiérrez-Kobeh, Laila
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7309628/
https://ncbi.nlm.nih.gov/pubmed/32312763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00963-19
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