ABC transporters and the hallmarks of cancer: roles in cancer aggressiveness beyond multidrug resistance

The ATP-binding cassette transporters (ABC transporters) have been intensely studied over the past 50 years for their involvement in the multidrug resistance (MDR) phenotype, especially in cancer. They are frequently overexpressed in both naive and post-treatment tumors, and hinder effective chemoth...

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Bibliografiske detaljer
Udgivet i:Cancer Biol Med
Main Authors: Muriithi, Wanjiru, Macharia, Lucy Wanjiku, Heming, Carlos Pilotto, Echevarria, Juliana Lima, Nyachieo, Atunga, Filho, Paulo Niemeyer, Neto, Vivaldo Moura
Format: Artigo
Sprog:Inglês
Udgivet: Compuscript 2020
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7309456/
https://ncbi.nlm.nih.gov/pubmed/32587767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20892/j.issn.2095-3941.2019.0284
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