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ABC transporters and the hallmarks of cancer: roles in cancer aggressiveness beyond multidrug resistance

The ATP-binding cassette transporters (ABC transporters) have been intensely studied over the past 50 years for their involvement in the multidrug resistance (MDR) phenotype, especially in cancer. They are frequently overexpressed in both naive and post-treatment tumors, and hinder effective chemoth...

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Detalhes bibliográficos
Publicado no:Cancer Biol Med
Main Authors: Muriithi, Wanjiru, Macharia, Lucy Wanjiku, Heming, Carlos Pilotto, Echevarria, Juliana Lima, Nyachieo, Atunga, Filho, Paulo Niemeyer, Neto, Vivaldo Moura
Formato: Artigo
Idioma:Inglês
Publicado em: Compuscript 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7309456/
https://ncbi.nlm.nih.gov/pubmed/32587767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20892/j.issn.2095-3941.2019.0284
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