Transcriptome analysis reveals a classical interferon signature induced by IFNλ4 in human primary cells

The IFNL4 gene is negatively associated with spontaneous and treatment-induced clearance of hepatitis C virus infection. The activity of IFNλ4 has an important causal role in the pathogenesis, but the molecular details are not fully understood. One possible reason for the detrimental effect of IFNλ4...

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Publicat a:Genes Immun
Autors principals: Lauber, C, Vieyres, G, Terczyńska-Dyla, E, Anggakusuma, Dijkman, R, Gad, H H, Akhtar, H, Geffers, R, Vondran, F W R, Thiel, V, Kaderali, L, Pietschmann, T, Hartmann, R
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7308733/
https://ncbi.nlm.nih.gov/pubmed/26066369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2015.23
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