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Structural mechanism underlying primary and secondary coupling between GPCRs and the Gi/o family
Heterotrimeric G proteins are categorized into four main families based on their function and sequence, Gs, Gi/o, Gq/11, and G12/13. One receptor can couple to more than one G protein subtype, and the coupling efficiency varies depending on the GPCR-G protein pair. However, the precise mechanism und...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7308389/ https://ncbi.nlm.nih.gov/pubmed/32572026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16975-2 |
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