Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2

Interacting with proteins is a crucial way for long noncoding RNAs (lncRNAs) to exert their biological responses. Here we report a high throughput strategy to characterize lncRNA interacting proteins in vivo by combining tobramycin affinity purification and mass spectrometric analysis (TOBAP-MS). Us...

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Vydáno v:Nat Commun
Hlavní autoři: Wang, Chunqing, Li, Yongmei, Yan, Shuai, Wang, Hao, Shao, Xianfeng, Xiao, Mingming, Yang, Baicai, Qin, Guoxuan, Kong, Ruirui, Chen, Ruibing, Zhang, Ning
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7308313/
https://ncbi.nlm.nih.gov/pubmed/32572027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16966-3
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