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Carbon nanoparticles induce endoplasmic reticulum stress around blood vessels with accumulation of misfolded proteins in the developing brain of offspring

Nano-particulate air pollution threatens developing brains and is epidemiologically related to neurodegenerative diseases involving deposition of misfolded proteins. However, the mechanism underlying developmental neurotoxicity by nanoparticles remains unknown. Here, we report that maternal exposure...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Onoda, Atsuto, Kawasaki, Takayasu, Tsukiyama, Koichi, Takeda, Ken, Umezawa, Masakazu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7308306/
https://ncbi.nlm.nih.gov/pubmed/32572058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66744-w
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