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Albumin-neprilysin fusion protein: understanding stability using small angle X-ray scattering and molecular dynamic simulations
Fusion technology is widely used in protein-drug development to increase activity, stability, and bioavailability of protein therapeutics. Fusion proteins, like any other type of biopharmaceuticals, need to remain stable during production and storage. Due to the high complexity and additional intram...
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| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7308280/ https://ncbi.nlm.nih.gov/pubmed/32572086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67002-9 |
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