Aprepitant Sensitizes Acute Myeloid Leukemia Cells to the Cytotoxic Effects of Cytosine Arabinoside in vitro and in vivo

PURPOSE: Acute myeloid leukemia (AML) is a complex malignancy characterized by the clonal expansion of immature myeloid precursors. The standard treatment for newly diagnosed AML is chemotherapy consisting of cytosine arabinoside (Ara-C) and anthracyclines with disappointing clinical outcomes and se...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Wu, Hongzhang, Cheng, Xurui, Huang, Feiyan, Shao, Gang, Meng, Yueming, Wang, Lingfei, Wang, Tao, Jia, Xiaoyuan, Yang, Tianxin, Wang, Xi, Fu, Caiyun
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7308242/
https://ncbi.nlm.nih.gov/pubmed/32606608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S244648
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