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Is the tryptophan codon of gene vif the Achilles’ heel of HIV-1?

To evaluate the impact of hypermutation on the HIV-1 dissemination at the population level we studied 7072 sequences HIV-1 gene vif retrieved from the public databank. From this dataset 854 sequences were selected because they had associated values of CD4+ T lymphocytes counts and viral loads and th...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Villanova, Fabiola, Barreiros, Marta, Leal, Élcio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7308096/
https://ncbi.nlm.nih.gov/pubmed/32570272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0225563
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