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The Achilles Heel of the Trojan Horse Model of HIV-1 trans-Infection

To ensure their survival, microbial pathogens have evolved diverse strategies to subvert host immune defenses. The human retrovirus HIV-1 has been proposed to hijack the natural endocytic function of dendritic cells (DCs) to infect interacting CD4 T cells in a process termed trans-infection. Althoug...

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Autors principals: Cavrois, Marielle, Neidleman, Jason, Greene, Warner C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430767/
https://ncbi.nlm.nih.gov/pubmed/18584030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000051
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