The cellular basis of protease-activated receptor 2–evoked mechanical and affective pain

Protease-activated receptor 2 (PAR2) has long been implicated in inflammatory and visceral pain, but the cellular basis of PAR2-evoked pain has not been delineated. Although PAR2-evoked pain has been attributed to sensory neuron expression, RNA-sequencing experiments show ambiguous F2rl1 mRNA detect...

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Gepubliceerd in:JCI Insight
Hoofdauteurs: Hassler, Shayne N., Kume, Moeno, Mwirigi, Juliet M., Ahmad, Ayesha, Shiers, Stephanie, Wangzhou, Andi, Ray, Pradipta R., Belugin, Serge N., Naik, Dhananjay K., Burton, Michael D., Vagner, Josef, Boitano, Scott, Akopian, Armen N., Dussor, Gregory, Price, Theodore J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7308051/
https://ncbi.nlm.nih.gov/pubmed/32352932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.137393
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