LGR4 deficiency results in delayed puberty through impaired Wnt/β-catenin signaling

The initiation of puberty is driven by an upsurge in hypothalamic gonadotropin-releasing hormone (GnRH) secretion. In turn, GnRH secretion upsurge depends on the development of a complex GnRH neuroendocrine network during embryonic life. Although delayed puberty (DP) affects up to 2% of the populati...

詳細記述

保存先:
書誌詳細
出版年:JCI Insight
主要な著者: Mancini, Alessandra, Howard, Sasha R., Marelli, Federica, Cabrera, Claudia P., Barnes, Michael R., Sternberg, Michael J.E., Leprovots, Morgane, Hadjidemetriou, Irene, Monti, Elena, David, Alessia, Wehkalampi, Karoliina, Oleari, Roberto, Lettieri, Antonella, Vezzoli, Valeria, Vassart, Gilbert, Cariboni, Anna, Bonomi, Marco, Garcia, Marie Isabelle, Guasti, Leonardo, Dunkel, Leo
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2020
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7308048/
https://ncbi.nlm.nih.gov/pubmed/32493844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.133434
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料