Imidazole–Imidazole Hydrogen Bonding in the pH-Sensing Histidine Side Chains of Influenza A M2

[Image: see text] The arrangement of histidine side chains in influenza A M2 tetramer determines their pK(a) values, which define pH-controlled proton conduction critical to the virus lifecycle. Both water-associated and hydrogen-bonded imidazole–imidazolium histidine quaternary structures have been...

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Bibliografske podrobnosti
izdano v:J Am Chem Soc
Main Authors: Movellan, Kumar Tekwani, Wegstroth, Melanie, Overkamp, Kerstin, Leonov, Andrei, Becker, Stefan, Andreas, Loren B.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2020
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307898/
https://ncbi.nlm.nih.gov/pubmed/31970979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b10984
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