An Inhibitor of the Mitochondrial Permeability Transition Pore is Toxic in Neonatal Mice and lacks Therapeutic Efficacy Following Neonatal Hypoxia Ischemia in Mice

Neonatal hypoxic ischemic (HI) brain injury causes lifelong neurologic disability. Therapeutic hypothermia (TH) is the only approved therapy that partially mitigates mortality and morbidity. Therapies specifically targeting HI-induced brain cell death are currently lacking. Intracellular calcium dys...

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Detaylı Bibliyografya
Yayımlandı:Neuroscience
Asıl Yazarlar: Fang, Jing, Chavez-Valdez, Raul, Flock, Debbie L., Avaritt, Oliver, Saraswati, Manda, Robertson, Courtney, Martin, Lee J., Northington, Frances J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307715/
https://ncbi.nlm.nih.gov/pubmed/30849447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2019.02.030
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