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An Inhibitor of the Mitochondrial Permeability Transition Pore is Toxic in Neonatal Mice and lacks Therapeutic Efficacy Following Neonatal Hypoxia Ischemia in Mice
Neonatal hypoxic ischemic (HI) brain injury causes lifelong neurologic disability. Therapeutic hypothermia (TH) is the only approved therapy that partially mitigates mortality and morbidity. Therapies specifically targeting HI-induced brain cell death are currently lacking. Intracellular calcium dys...
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| 出版年: | Neuroscience |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7307715/ https://ncbi.nlm.nih.gov/pubmed/30849447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2019.02.030 |
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