Dual oxidase 1 limits the IFNγ-associated antitumor effect of macrophages

BACKGROUND: Macrophages play pivotal roles in tumor progression and the response to anticancer therapies, including radiotherapy (RT). Dual oxidase (DUOX) 1 is a transmembrane enzyme that plays a critical role in oxidant generation. METHODS: Since we found DUOX1 expression in macrophages from human...

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Bibliographic Details
Published in:J Immunother Cancer
Main Authors: Meziani, Lydia, Gerbé de Thoré, Marine, Hamon, Pauline, Bockel, Sophie, Louzada, Ruy A, Clemenson, Céline, Corre, Raphaël, Liu, Winchygn, Dupuy, Corinne, Mondini, Michele, Deutsch, Eric
Format: Artigo
Language:Inglês
Published: BMJ Publishing Group 2020
Subjects:
Immune Cell Therapies and Immune Cell Engineering
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307581/
https://ncbi.nlm.nih.gov/pubmed/32571996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000622
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