Pickering emulsions with ethiodized oil and nanoparticles for slow release of intratumoral anti-CTLA4 immune checkpoint antibodies

BACKGROUND: Intratumorous immunotherapy for cancer is currently thriving. The aim of such local strategy is to improve the therapeutic index of these treatments, for higher on-target/on-tumor activity and less on-target/off-tumor adverse events. Strategies allowing for slow release of anti-CTLA4 in...

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Veröffentlicht in:J Immunother Cancer
Hauptverfasser: Tselikas, Lambros, de Baere, Thierry, Isoardo, Thomas, Susini, Sandrine, Ser-Le Roux, Karine, Polrot, Mélanie, Adam, Julien, Rouanne, Mathieu, Zitvogel, Laurence, Moine, Laurence, Deschamps, Fréderic, Marabelle, Aurélien
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2020
Schlagworte:
Oncolytic and Local Immunotherapy
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307549/
https://ncbi.nlm.nih.gov/pubmed/32571995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000579
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