The mRNA-binding protein IGF2BP1 maintains intestinal barrier function by up-regulating occludin expression

Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) is an mRNA-binding protein that has an oncofetal pattern of expression. It is also expressed in intestinal tissue, suggesting that it has a possible role in intestinal homeostasis. To investigate this possibility, here we generated Villin...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Singh, Vikash, Gowda, Chethana P., Singh, Vishal, Ganapathy, Ashwinkumar S., Karamchandani, Dipti M., Eshelman, Melanie A., Yochum, Gregory S., Nighot, Prashant, Spiegelman, Vladimir S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2020
Fag:
Accelerated Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307209/
https://ncbi.nlm.nih.gov/pubmed/32385106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC120.013646
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