Innate Intracellular Antiviral Responses Restrict the Amplification of Defective Virus Genomes of Parainfluenza Virus 5

During the replication of parainfluenza virus 5 (PIV5), copyback defective virus genomes (DVGs) are erroneously produced and are packaged into “infectious” virus particles. Copyback DVGs are the primary inducers of innate intracellular responses, including the interferon (IFN) response. While DVGs c...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Wignall-Fleming, Elizabeth B., Vasou, Andri, Young, Dan, Short, John A. L., Hughes, David J., Goodbourn, Steve, Randall, Richard E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2020
Soggetti:
Virus-Cell Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307174/
https://ncbi.nlm.nih.gov/pubmed/32295916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00246-20
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