Innate Intracellular Antiviral Responses Restrict the Amplification of Defective Virus Genomes of Parainfluenza Virus 5

During the replication of parainfluenza virus 5 (PIV5), copyback defective virus genomes (DVGs) are erroneously produced and are packaged into “infectious” virus particles. Copyback DVGs are the primary inducers of innate intracellular responses, including the interferon (IFN) response. While DVGs c...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Wignall-Fleming, Elizabeth B., Vasou, Andri, Young, Dan, Short, John A. L., Hughes, David J., Goodbourn, Steve, Randall, Richard E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307174/
https://ncbi.nlm.nih.gov/pubmed/32295916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00246-20
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