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PCV2 Induces Reactive Oxygen Species To Promote Nucleocytoplasmic Translocation of the Viral DNA Binding Protein HMGB1 To Enhance Its Replication

Porcine circovirus type 2 (PCV2) is an important swine pathogen that causes significant economic losses to the pig industry. PCV2 interacts with host cellular factors to regulate its replication. High-mobility-group box 1 (HMGB1) protein, a major nonhistone protein in the nucleus, was recently disco...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Sun, Renjie, Sun, Siqi, Zhang, Yikai, Zhou, Yingshan, Shan, Ying, Li, Xiaoliang, Fang, Weihuan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307167/
https://ncbi.nlm.nih.gov/pubmed/32321806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00238-20
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