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Effects of Tumor Necrosis Factor on Viral Replication and Pulmonary Inflammation during Acute Mouse Adenovirus Type 1 Respiratory Infection
CD8 T cells contribute to effective clearance of mouse adenovirus type 1 (MAV-1) and to virus-induced pulmonary inflammation. We characterized effects of a CD8 T cell effector, TNF, on MAV-1 pathogenesis. TNF inhibited MAV-1 replication in vitro. TNF deficiency or immunoneutralization had no effect...
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| Publicado no: | Virology |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7306826/ https://ncbi.nlm.nih.gov/pubmed/32560900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2020.05.004 |
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