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Age-Dependent Effects of Immunoproteasome Deficiency on Mouse Adenovirus Type 1 Pathogenesis

Acute respiratory infection with mouse adenovirus type 1 (MAV-1) induces activity of the immunoproteasome, an inducible form of the proteasome that shapes CD8 T cell responses by enhancing peptide presentation by major histocompatibility complex (MHC) class I. We used mice deficient in all three imm...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Chandrasekaran, Adithya, Adkins, Laura J., Seltzer, Harrison M., Pant, Krittika, Tryban, Stephen T., Molloy, Caitlyn T., Weinberg, Jason B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639286/
https://ncbi.nlm.nih.gov/pubmed/31092582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00569-19
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