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Studies on the mechanism of general anesthesia
Inhaled anesthetics are a chemically diverse collection of hydrophobic molecules that robustly activate TWIK-related K(+) channels (TREK-1) and reversibly induce loss of consciousness. For 100 y, anesthetics were speculated to target cellular membranes, yet no plausible mechanism emerged to explain...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7306821/ https://ncbi.nlm.nih.gov/pubmed/32467161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2004259117 |
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