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Nanoparticle delivery of immunostimulatory oligonucleotides enhances response to checkpoint inhibitor therapeutics

The recent advent of immune checkpoint inhibitor (CPI) antibodies has revolutionized many aspects of cancer therapy, but the efficacy of these breakthrough therapeutics remains limited, as many patients fail to respond for reasons that still largely evade understanding. An array of studies in human...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Buss, Colin G., Bhatia, Sangeeta N.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306768/
https://ncbi.nlm.nih.gov/pubmed/32493746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2001569117
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