Structural and catalytic effects of surface loop-helix transplantation within haloalkane dehalogenase family

Engineering enzyme catalytic properties is important for basic research as well as for biotechnological applications. We have previously shown that the reshaping of enzyme access tunnels via the deletion of a short surface loop element may yield a haloalkane dehalogenase variant with markedly modifi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Comput Struct Biotechnol J
Päätekijät: Marek, Martin, Chaloupkova, Radka, Prudnikova, Tatyana, Sato, Yukari, Rezacova, Pavlina, Nagata, Yuji, Kuta Smatanova, Ivana, Damborsky, Jiri
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Research Network of Computational and Structural Biotechnology 2020
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306515/
https://ncbi.nlm.nih.gov/pubmed/32612758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.05.019
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