Structural and catalytic effects of surface loop-helix transplantation within haloalkane dehalogenase family

Engineering enzyme catalytic properties is important for basic research as well as for biotechnological applications. We have previously shown that the reshaping of enzyme access tunnels via the deletion of a short surface loop element may yield a haloalkane dehalogenase variant with markedly modifi...

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Publicat a:Comput Struct Biotechnol J
Autors principals: Marek, Martin, Chaloupkova, Radka, Prudnikova, Tatyana, Sato, Yukari, Rezacova, Pavlina, Nagata, Yuji, Kuta Smatanova, Ivana, Damborsky, Jiri
Format: Artigo
Idioma:Inglês
Publicat: Research Network of Computational and Structural Biotechnology 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306515/
https://ncbi.nlm.nih.gov/pubmed/32612758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.05.019
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