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Bacterial phytochrome as a scaffold for engineering of receptor tyrosine kinases controlled with near-infrared light

Optically controlled receptor tyrosine kinases (opto-RTKs) allow regulation of RTK signaling using light. Until recently, the majority of opto-RTKs were activated with blue-green light. Fusing a photosensory core module of Deinococcus radiodurans bacterial phytochrome (DrBphP-PCM) to the kinase doma...

Полное описание

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Библиографические подробности
Опубликовано в: :J Mol Biol
Главные авторы: Leopold, Anna V., Pletnev, Sergei, Verkhusha, Vladislav V.
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306426/
https://ncbi.nlm.nih.gov/pubmed/32302608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.04.005
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