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Bacterial phytochrome as a scaffold for engineering of receptor tyrosine kinases controlled with near-infrared light

Optically controlled receptor tyrosine kinases (opto-RTKs) allow regulation of RTK signaling using light. Until recently, the majority of opto-RTKs were activated with blue-green light. Fusing a photosensory core module of Deinococcus radiodurans bacterial phytochrome (DrBphP-PCM) to the kinase doma...

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Bibliographische Detailangaben
Veröffentlicht in:J Mol Biol
Hauptverfasser: Leopold, Anna V., Pletnev, Sergei, Verkhusha, Vladislav V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306426/
https://ncbi.nlm.nih.gov/pubmed/32302608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.04.005
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