Evaluating the Utility of Polygenic Risk Scores in Identifying High-Risk Individuals for Eight Common Cancers

BACKGROUND: Genome-wide association studies have identified common genetic risk variants in many loci associated with multiple cancers. We sought to systematically evaluate the utility of these risk variants in identifying high-risk individuals for eight common cancers. METHODS: We constructed polyg...

Full description

Saved in:
Bibliographic Details
Published in:JNCI Cancer Spectr
Main Authors: Jia, Guochong, Lu, Yingchang, Wen, Wanqing, Long, Jirong, Liu, Ying, Tao, Ran, Li, Bingshan, Denny, Joshua C, Shu, Xiao-Ou, Zheng, Wei
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306192/
https://ncbi.nlm.nih.gov/pubmed/32596635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jncics/pkaa021
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items