Novel likely disease-causing CLN5 variants identified in Pakistani patients with neuronal ceroid lipofuscinosis

BACKGROUND: Neuronal ceroid lipofuscinosis (NCL) is a hereditary lysosomal storage disease with progressive brain neurodegeneration. Mutations in ceroid lipofuscinosis neuronal protein 5 (CLN5) cause CLN5 disease, a severe condition characterized by seizures, visual failure, motor decline, and progr...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Neurol Sci
Main Authors: Azad, Beenish, Efthymiou, Stephanie, Sultan, Tipu, Scala, Marcello, Alvi, Javeria Raza, Neuray, Caroline, Dominik, Natalia, Gul, Asma, Houlden, Henry
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306150/
https://ncbi.nlm.nih.gov/pubmed/32302805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jns.2020.116826
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker